Blueberry muffin rash rubella

In most cases, the illness regresses without complications within 4-weeks. The term blueberry muffin rash is used to describe the clinical presentation of dermal extramedullary hematopoiesis. Blueberry muffin syndrome DermNet NZ What is blueberry muffin syndrome? Jul 0 20Yes, the description is consistent with a blueberry muffin rash.

This rash appears in various congenital infections like rubella, congenital syphilis, rhesus incompatibility, parvovirus B1 cytomegalovirus, toxoplasmosis and Binfection. These are due to the presence of clusters of blood-producing cells in the skin (extramedullary erythropoiesis or bleeding into the skin ( purpura ) or spreading cancer ( metastases ).

Congenital Rubella Syndrome with Blueberry Muffin Lesions

From to wk, the risk of infection is about 2 with minimal chances of congenital defects. From to wk, the risk of infection is about 6 and risk of defects, about 50. This rash occurs because of extramedullary hematopoiesis in sites of different magnitudes and extensions.

In congenital rubella, the blueberry muffin rash is observed at birth or rarely some months later. The common culprits of this rash include a TORCH (toxoplasmosis, other agents, rubella, cytomegalovirus, herpes) infection or hematologic dyscrasia. Blueberry muffin rash appears round in shape but often it appears oval in shape. Blueberry muffin syndrome is the descriptive term used when an infant is born with multiple bluepurple marks or nodules in the skin. Infection occurring in the first trimester causes congenital rubella infection in 9 with almost a 1risk of congenital defects.

The term originated in the early 1960s when the rubella epidemic occurred in this country.
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